The following instruction shows how to enable multiple instances of DEWESoft exe to run simultaneously on the same machine. While on pre-Win8 OS this is straight-forward: 

  1.  enable the option in DEWESoft (under global settings),
  2.  disable UAC (Control Panel > 'Change User Account Control settings') to allow Plugin registration.

On Windows 8 and higher additional step is needed that prevents running admins in 'Admin Approval Mode'. First, go to Control Panel > System and Security > Administrative Tools: 

Go to 'Local Security Policy': 

Under 'Security options', disable following: »User Account Control: Run all administrators in Admin Approval Mode«: 

That enables plugins to be registered in all instances of DEWESoft.

Please note that Dewesoft instances must be placed in a different folder, so there are two different system folders.